The Dangme East is located in the Eastern part of the Greater Accra Region within Latitudes 5°45 south and 6°00 north and from Longitude 0°20 west to 0°35 East. It shares common boundaries with North Tongu District at the North, south Tongu District and Dangme West District at the east and West respectively. At the south is the Gulf of Guinea, which stretches over 45 kilometres (27.9 miles).

The District covers a total land area of about 909 sq km (350 sq miles) about 28% of the total area of the Greater Accra Region.

Ada Foah, the District Capital is located at the south-eastern part, about 20km off the Accra-Aflao road, along the coast and about 2km from the Volta River Estuary. Other major settlements are Big Ada, Kasseh, Got, Anyamam, Lolonya, Akplabanya, Wokumagbe and Koluedor.